Santo Tomé Vacations

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Your Santo Tomé Vacation

Amazing adventures await when you reserve a Santo Tomé vacation package. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this awesome city. You'll want to sightsee during your trip to Santo Tomé. Swing by leading attractions such as National University of the Littoral, Cervecería Santa Fe and Catedral Metropolitana. Stop daydreaming and start adventuring. Explore the wide range of options on Expedia today and finally put your Santo Tomé vacation plans into gear!

Discover the most popular places to visit in Santo Tomé

Santo Tomé Hotel Deals

Hotel de Campo Colon

Hotel de Campo Colon

3.5 out of 5
Autopista Santa Fe - Rosario / KM 153, Colectora Norte, Santo Tomé, Santa Fe
Hotel is OK, but not worth the price
"Pleasant and quiet rooms. Clean. But not a very friendly staff. The cafeteria has very few food/drink options, and it has a fly (the insect) problem. Oh, they overcharged my stay by 20% based on what Expedia quoted me, so read the bill before checking out..."

Reviewed on Feb 5, 2017

Hotel de Campo Colon
InterTower Hotel

InterTower Hotel

4 out of 5
San Jeronimo 2779, Santa Fe, Santa Fe
Fully refundableReserve now, pay when you stay
$95 nightly
The price is $95 total per night from Oct 26 to Oct 27
$95 total
Oct 26 - Oct 27
8.8/10 Excellent! (206 reviews)
"The hotel has good amenities. Staff very friendly. Area is ok but it did not feel so secure to walk outside at night."

Reviewed on Oct 8, 2025

InterTower Hotel
Castelar Hotel Santa Fe

Castelar Hotel Santa Fe

3 out of 5
25 de Mayo 2349, Santa Fe, Santa Fe
Fully refundableReserve now, pay when you stay
7.2/10 Good! (87 reviews)
"Great area for walking and dining. Friendly and helpful staff."

Reviewed on Jul 12, 2025

Castelar Hotel Santa Fe
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Santo Tomé Essential Information

Language
Spanish
Currency
Argentine pesos
Local Welcome
¡Hola!
Local Goodbye
Adiós
Closest Airport
Sauce Viejo Airport (SFN)
Population
59,100
Max Temp Winter
65ºF
Max Temp Summer
90ºF
Top Sights
Cervecería Santa Fe, Museo Historico Comunal y de la Colonizacion Judia Rabino Aaron Halevi Goldman and Historical Provincial Museum

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Frequently asked questions

How much does a Santo Tomé vacation package cost?
Offering great value package deals on Expedia, you'll be thrilled with how little a vacation to Santo Tomé costs! Expedia's packages simplify travel planning and maximize your savings.
What are the cheapest months to go to Santo Tomé?
If you'd like to snag a cheap Santo Tomé vacation package, consider traveling in March, May and December. You'll usually find lower rates on hotels and airfares during these months — ideal for budget-conscious travelers.
How many days is enough for Santo Tomé?
Usually, a handful of days is enough to explore the top sights during your Santo Tomé vacation. However, if you want to have more time to kick back or take day tours, consider extending your itinerary.
How to find the best Santo Tomé package deals?
Finding a cheap Santo Tomé package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply some filters and see what's available. You can fine-tune your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most economical Santo Tomé package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.
Is it cheaper to book a Santo Tomé vacation as a package?
You can enjoy significant savings on your Santo Tomé retreat by booking a tailored vacation package. Click on the "Package" heading, then select your travel dates and destination to browse some great flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.
When to book a vacation package to Santo Tomé?
If you're considering a spontaneous Santo Tomé trip, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can find incredible deals on your hotels and flights by booking ahead.
Does Expedia offer Book Now, Pay Later Santo Tomé vacation packages?
If you're anything like us, you love jet-setting around the world but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Santo Tomé trip across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.