Santo Tomé Vacations

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Your Santo Tomé Vacation

Amazing adventures await when you reserve a Santo Tomé vacation package. Whether you're a foodie, art buff or just a traveler who loves discovering new places, there's something for everyone in this awesome city. You'll want to sightsee during your trip to Santo Tomé. Swing by leading attractions such as National University of the Littoral, Cervecería Santa Fe and Catedral Metropolitana. Stop daydreaming and start adventuring. Explore the wide range of options on Expedia today and finally put your Santo Tomé vacation plans into gear!

Discover the most popular places to visit in Santo Tomé

Museo De Arte Contemporaneo

You can spend time studying the exhibits at Museo De Arte Contemporaneo during your travels in Santo Tomé. Experience the area's live music and museums.

Santo Tomé Hotel Deals

Hotel de Campo Colon

Autopista Santa Fe - Rosario / KM 153 Santo Tomé Santa Fe

Hotel is OK, but not worth the price

Pleasant and quiet rooms. Clean. But not a very friendly staff. The cafeteria has very few food/drink options, and it has a fly (the insect) problem. Oh, they overcharged my stay by 20% based on what Expedia quoted me, so read the bill before checking out...

Reviewed on Feb 5, 2017

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InterTower Hotel

San Jeronimo 2779 Santa Fe Santa Fe

Fully refundableReserve now, pay when you stay

$88 nightly

$88 total

Dec 28 - Dec 29

8.8/10 Excellent! (210 reviews)

Very good

Reviewed on Nov 20, 2025

Los Silos Hotel

Dique I Puerto Santa Fe Santa Fe Santa Fe

Fully refundableReserve now, pay when you stay

$108 nightly

$108 total

Dec 14 - Dec 15

9.2/10 Wonderful! (27 reviews)

Muy original, un hotel construido en un viejo Silo

Reviewed on Mar 31, 2024

See all 64 properties in Santo Tomé

Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Find the Best Santo Tomé Vacation Packages

Santo Tomé Essential Information

Language	Spanish
Currency	Argentine pesos
Local Welcome	¡Hola!
Local Goodbye	Adiós
Closest Airport	Sauce Viejo Airport (SFN)
Population	59,100
Max Temp Winter	65ºF
Max Temp Summer	90ºF
Top Sights	Cervecería Santa Fe, Museo Historico Comunal y de la Colonizacion Judia Rabino Aaron Halevi Goldman and Historical Provincial Museum

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Frequently asked questions

How much does a Santo Tomé vacation package cost?

Offering great value package deals on Expedia, you'll be thrilled with how little a vacation to Santo Tomé costs! Expedia's packages simplify travel planning and maximize your savings.

What are the cheapest months to go to Santo Tomé?

If you'd like to snag a cheap Santo Tomé vacation package, consider traveling in March, May and December. You'll usually find lower rates on hotels and airfares during these months — ideal for budget-conscious travelers.

How many days is enough for Santo Tomé?

Usually, a handful of days is enough to explore the top sights during your Santo Tomé vacation. However, if you want to have more time to kick back or take day tours, consider extending your itinerary.

How to find the best Santo Tomé package deals?

Finding a cheap Santo Tomé package deal is a cinch with Expedia. Once you've entered your destination and preferred dates under our "Packages" tab, set your budget, apply some filters and see what's available. You can fine-tune your search by "Amenities," "Property type," "Popular locations" and more. Sort the results by "Price: low to high" to view the most economical Santo Tomé package deals. Want a simple trick to score the biggest savings? Have some flexibility with your departure dates and consider going away on a weekday, when prices are generally lower.

Is it cheaper to book a Santo Tomé vacation as a package?

You can enjoy significant savings on your Santo Tomé retreat by booking a tailored vacation package. Click on the "Package" heading, then select your travel dates and destination to browse some great flight and hotel prices. Bundle everything into a great-value package and you can save hundreds of dollars. Consider adding a car rental and you may score a better deal.

When to book a vacation package to Santo Tomé?

If you're considering a spontaneous Santo Tomé trip, browse our last-minute deals that can be booked up to one week before you take off. Prefer not to wait until the last minute? You can find incredible deals on your hotels and flights by booking ahead.

Does Expedia offer Book Now, Pay Later Santo Tomé vacation packages?

If you're anything like us, you love jet-setting around the world but don't love the big price tag that can sometimes come with it. That's why we've created Book Now, Pay Later vacations. With the help of online lender Affirm, you can break down the overall cost of your Santo Tomé trip across 3, 6 or 12 months. There are also no hidden costs or late payment fees, so you can snap up cheap vacation packages with payment plans as soon as you spot them.

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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.